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Small Drug Uses: Amitriptyline is a tricyclic antidepressant that increases the activity of certain chemicals in the brain (norepinephrine, serotonin), which help improve mood.
Drug Class and Mechanism: Amitriptyline is a tricyclic antidepressant. How tricyclic antidepressants improve depression symptoms is not fully understood. They are thought to increase the activity of certain chemicals in the brain (norepinephrine, serotonin), which help improve mood.
Missed Dose: If you miss a dose of Amitriptyline and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Warnings Precautions: Do not use Amitriptyline if:
- you are allergic to any ingredient in Amitriptyline;
- you are currently taking or have taken a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine, selegiline) within the last 14 days;
- you are taking antihistamines (e.g., diphenhydramine), cisapride, droperidol, a ketolide (e.g., telithromycin) , a macrolide (e.g., erythromycin), mibefradil, or pimozide;
- you are recovering from a heart attack.
Contact your doctor or health care provider right away if any of these apply to you.
Important :- Amitriptyline may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Amitriptyline . Using Amitriptyline alone, with other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Avoid drinking alcohol or taking other medicines that cause drowsiness (e.g., sedatives, tranquilizers) while taking Amitriptyline. Amitriptyline will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
- Amitriptyline may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Involuntary and uncontrollable movements may develop in patients taking Amitriptyline . Occurrence is highest among the elderly, especially women. The risk of developing these involuntary movements and the likelihood they will become permanent are increased with long-term use and with high doses. However, it is possible to develop these symptoms after short-term use at low doses. Contact your health care provider at once if any of the following occur: involuntary movements of the tongue, face, mouth, or jaw (e.g., protrusion of tongue, puffing of cheeks, puckering of mouth, chewing movements), sometimes accompanied by involuntary movements of the arms and legs.
- Do not become overheated in hot weather or during exercise or other activities since heatstroke may occur.
- Children, teenagers, and young adults who take Amitriptyline may be at increased risk for suicidal thoughts or actions. Watch all patients who take Amitriptyline closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Pregnancy and breast-feeding: Amitriptyline has been shown to cause harm to the human fetus. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Amitriptyline during pregnancy. Amitriptyline is excreted in the breast milk. Do not breast-feed while taking Amitriptyline.
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While most antidepressants are taken once a day, some people have a problem remembering to take their medication if it is prescribed for more than once each day. If this is a problem for you, your doctor may prescribe a longer-acting antidepressant such as Wellbutrin XL (bupropion) or Paxil CR (paroxetine)... Amitriptyline online UK
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